radio telemetry device data Search Results


radio telemetry devices t2j  (Konigsberg Instruments)
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Konigsberg Instruments radio telemetry devices t2j
Radio Telemetry Devices T2j, supplied by Konigsberg Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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radio-telemetry device  (Transoma Medical Inc)
90
Transoma Medical Inc radio-telemetry device
Radio Telemetry Device, supplied by Transoma Medical Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ecg telemetry devices  (Data Sciences International)
86
Data Sciences International ecg telemetry devices
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
Ecg Telemetry Devices, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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telemetry devices  (Data Sciences International)
86
Data Sciences International telemetry devices
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
Telemetry Devices, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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telemetry devices - by Bioz Stars, 2026-06
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m01 telemetry device  (Data Sciences International)
86
Data Sciences International m01 telemetry device
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
M01 Telemetry Device, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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wireless eeg telemetry system  (Data Sciences International)
86
Data Sciences International wireless eeg telemetry system
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
Wireless Eeg Telemetry System, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hd s10 radiotelemetry probes  (Data Sciences International)
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Data Sciences International hd s10 radiotelemetry probes
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
Hd S10 Radiotelemetry Probes, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cri pt telemetry devices  (Data Sciences International)
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Data Sciences International cri pt telemetry devices
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
Cri Pt Telemetry Devices, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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wireless eeg emg telemetry devices  (Data Sciences International)
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Data Sciences International wireless eeg emg telemetry devices
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
Wireless Eeg Emg Telemetry Devices, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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wireless telemetry device  (Data Sciences International)
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Data Sciences International wireless telemetry device
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
Wireless Telemetry Device, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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indwelling radio telemetry device  (Data Sciences International)
86
Data Sciences International indwelling radio telemetry device
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
Indwelling Radio Telemetry Device, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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radio telemetry device  (Data Sciences International)
86
Data Sciences International radio telemetry device
( A ) Left: Representative telemetered <t>ECG</t> traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced <t>electrocardiographic</t> responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.
Radio Telemetry Device, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


( A ) Left: Representative telemetered ECG traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced electrocardiographic responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.

Journal: JCI Insight

Article Title: Enrichment of mutant calmodulin protein in a murine model of a human calmodulinopathy

doi: 10.1172/jci.insight.185524

Figure Lengend Snippet: ( A ) Left: Representative telemetered ECG traces recorded in ambulatory male mice. Right: Signal-averaged ECGs obtained by overlaying all consecutive cycles recorded within 5- to 10-second intervals, using QRS maximum or minimum for alignment. Lower rows show superimposed QRS complexes at expanded time scales. ( B ) Scatterplots of RR, QRS, and QT c intervals. Each dot represents the 12-hour (dark or light cycle) or 24-hour (all day) average in a single animal. Data are from 10 Calm1 +/+ , 9 Calm1 N98S/+ , and 9 Calm1 N98S/N98S mice. All populations were normally distributed. Horizontal lines superimposed on dots depict mean and SEM. * P ≤ 0.0118 vs. Calm1 +/+ ; † P ≤ 0.0144 vs. Calm1 N98S/+ . ECG measures were modeled by a repeated measures linear model with terms for genotype, time period, and the genotype by time period interaction. An unstructured covariance matrix was used. ( C ) Example of a spontaneous occurrence of a BVT in an ambulatory Calm1 N98S/N98S mouse. ( D ) Ventricular arrhythmia scores in and percentage of ambulatory mice presenting with at least 1 episode of nonsustained (duration > 3 and < 15 s) or sustained (duration > 15 s) BVT within 24 hours of continuous ECG recording. * P ≤ 0.0325 vs. Calm1 +/+ ; † P ≤ 0.0294 vs. Calm1 N98S/+ . P values by Fisher’s exact and χ 2 tests. ( E ) Examples of stress-induced electrocardiographic responses in ambulatory mice. ( F ) Ventricular arrhythmia scores and percentage of ambulatory mice developing BVT within 1 hour following a cage switch. Data are from 8 Calm1 +/+ , 9 Calm1 N98S/+ , and 8 Calm1 N98S/N98S mice. * P = 0.0002 vs. Calm1 +/+ ; † P ≤ 0.016 vs. Calm1 N98S/+ ; $ P = 0.0078 vs. before cage switch. P values for comparisons of proportions after cage switch between genotypes by Fisher’s exact test. P values for change in proportions by the Sign test.

Article Snippet: In brief, ECG telemetry devices (F10, Data Science International) were implanted intra-abdominally under isoflurane anesthesia, and recordings were initiated 2–3 days after recovery from surgery.

Techniques: